DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS

File: 123096_sep96_decls1_0041.txt
Page: 0041
Total Pages: 109

Subject: DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS       

Unit: OTSG        

Parent Organization: HSC         

Box  ID: BX003203

Folder Title: DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS                                       

Document Number:          1

Folder Seq  #:         21





                                    UNCLASSIFIED
                                             "C!;


          had a mortality of 60%. With tracheostomy and ventilatory

          assistance, fatalities should be <5%. Intensive and prolonged

          nursing care may be required for recovery (which may take several

          weeks or even months).




              @ITOXIN

              in isolated cases of foodborne botulism, circulating toxin is

          usually present, perhaps due to continued absorption through the

          gut wall. Equine antitoxin has been used in these circumstances,

          and is probably helpful. After aerosol exposure, it is unknown

          whether toxin circulates or antitoxin would be therapeutically

          useful after onset of symptoms. However, administration of

          antitoxin is reasonable if disease has not progressed to a stable

          state.




              A human pentavalent antitoxin produced by plasmapheresis of

          toxoid vaccinees is available in very limited quantities. It is an

          Investigational New Drug (IND) and has never been tested for

          efficacy. Formal safety and pharmacokinetic studies are in

          progress. This product is useful only for highly specialized

          indications, and should not be considered as generally available.

          There is no prospect for additional human antitoxin to be produced

          and made available in the foreseeable future.



                                         16           CLASSIFIED [3y:      SOUM'(;ES
                                                      DECLi@,$SIFY ON@ C.)ADR
                                   UNCLASSIFIED
                                         ,RF"@:F

Document 109 f:/Week-36/BX003203/DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS/detection of medical defense against biological :1217960927452
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003203
Unit = OTSG
Parent Organization = HSC
Folder Title = DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS
Folder Seq # = 21
Subject = DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 17-DEC-1996