DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS

File: 123096_sep96_decls1_0040.txt
Page: 0040
Total Pages: 109

Subject: DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS       

Unit: OTSG        

Parent Organization: HSC         

Box  ID: BX003203

Folder Title: DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS                                       

Document Number:          1

Folder Seq  #:         21




                                                     UNCLASSIFIED
                                                    gpeREcf

                The edrophonium (tensilon) test may be transiently positive in botulism. Other considerations


                include enteroviral infections; but in these patients, fever is present, paralysis is often


                asymmetrical, and the cerebrospinal fluid is abnormal. In the present setting, it will be


                necessary to distinguish nerve-agent and atropine poisoning from bo@um intoxication.


                ]3riefly, organophosphate nerve agent poisoning results in miotic pupils and copious


                secretions. In atropine poisoning, the pupils are dilated and mucous membranes are dry, but


                central nervous system excitation with hallucinations and demum is present. See Section IV


                for a more comprehensive differential.


                       3. S=ific Laboral= Diagnosis


                       Detection of toxin in serum or gastric contents from cases of foodbome botulism is


                often feasible by mouse inoculation. In the case of inhalation botulism, toxin may well be


                cleared from the blood by the time symptoms are noted. Nevertheless, serum should be


                obtained from representative cases for such attempts. Survivors probably will not develop an


                antibody response due to the small amount of toxin necessary to cause death. See Section UI


                for details of sample collection and pr      g.


                       C. THER"Y


                       Respiratory failure secondary to paralysis of respiratory muscles is the most serious


                complication and, generally, the cause of death. Reported cases of botulism prior to 1950


                                                                                                               CLS
                                                              is
                                                                             BY:
                                                   UNCLASSIFIED

Document 109 f:/Week-36/BX003203/DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS/detection of medical defense against biological :1217960927452
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003203
Unit = OTSG
Parent Organization = HSC
Folder Title = DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS
Folder Seq # = 21
Subject = DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 17-DEC-1996