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Araneta, Maria Rosario G. et al. Goldenhar Syndrome Among Infants Born in Military Hospitals to Gulf War Veterans. Teratology 1997; 56: 244-251.

Because press reports in 1995 suggested an excess of a congenital malformation called Goldenhar syndrome among the children of Gulf War veterans (GWV), the authors searched for cases of this syndrome among infants conceived after the Gulf War and born to active duty military personnel in DoD hospitals. The offspring of all GWV were compared to those of a 50% sample of veterans who had not deployed to the Gulf (NDV). Seven children fulfilled the criteria for Goldenhar syndrome. Five were born to GWVs and 2 to NDVs. The prevalence was higher among GWVs’ infants, but the difference was not statistically significant. The observed prevalence was compared to the rates in Hawaii, Atlanta, and California and variations in these rates was discussed. Limitations of this study are: only births in military hospitals were studied, so the children of veterans who had left the military, of members of the reserve component, and of some active duty personnel were not counted; potential errors in classification of birth defects may have occurred; and, the small number of affected births resulted in very wide confidence intervals around the relative risk.

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