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File: 123096_sep96_decls23_0009.txt
Page: 0009
Total Pages: 52

Subject: DIAGNOSIS AND TREATMENT OF DISEASES OF IMPORTANCE               

Unit: OTSG        

Parent Organization: HSC         

Box  ID: BX003203

Folder Title: DIAGNOSIS AND TREATMENT OF DISEASES  1991PORTABLE FIELD PERSONNEL SHOWER SYSTEMS                

Document Number:          1

Folder Seq  #:         88









          VII.   Disposition:    A.    No complications:   limited duty                                         Congo Crimean Hemorrhagic FOVer (CCJIF)
                                       (consider EVAC).                                          1.   Communicability;
                                 B.    Complications: hospitalization     and
                                       EVAC.                                                          A.    Route:
           vil. Prognosis:       A.    Treated: excellent.                                                  1.     Ixodid tick f@o me species) bite:
                                 B.    Untreated: 30% complications, prolonged                              2.     Exposure to blood, secretions, or excrement of
                                       hospitalization and convalescence with                                      infected Patients. Aerosol transmission may
                                       occasional deaths due to endocarditis.                                      occur, as transmission to hospital staff has been
                                                                                                                   documented in the absence of direct patient
           IX.   Public health measures:                                                                           contact.
                 Locate contaminated products, if implicated, and destroy;                                  3.     Exposure to tissue r blood of infected animals.
                 educate troops not to drink or eat unpasteurized dairy                               B.    Isolation:
                 products; report to Preventive Medicine.      Not communicable                             1.     Strict isolation mandatory, to include contact,
                 from person to person.                                                                            blood, body fluids, and respiratory. This must
                                                                include strict precautions in handling of clinical
                                                                                                                   laboratory specimens.

                                                                                                      C.    Prophylaxis:
                                                                                                            1.     No prophylaxis of proven efficacy is available.
                                                                                                            2.     Hyperimmune convalescent erum:
                                                                                                                   a.   Isolated clinical reports suggest that
                                                                                                                        administration of hyperimmune convalescent
                                                                                                                        human serum may be protective. Definitive
                                                                                                                        indications and dosage regimen have not been
                                                                                                                        established.
                                                                                                                   b.   250 ml administered IV over 1 to 2 hours,
                                                                                                                        possibly repeated once in 12 hours ay
                                                                                                                        beneficial.
roblems include:
                                                                                                                        i.  Inability to ascertain antiviral titers
                                                                                                                            in transfused serum.
                                                                                                                        ii. Hypersensitivity reactions.
                                                                                                                        iii. Transmission of other blood-b,r,,
                                                                                                                            illnesses,
                                                                                                            3.     Ribavirin:
                                                                                                                   a.   Ribavirin, an antiviral drug, may be effec-
                                                                                                                        tive. Definitive clinical studies have not
                                                                                                                        yet been accomplished but preliminary studies
                                                                                                                        show promise.
                                                                                                                   b.   Post exposure Prophylaxis should be strongly
                                                                                                                        cons idered for health care workers and
                                                                                                                        transporting Personnel involved in caring for
                                                                                        patients with CCHF. Prophylaxis should be
                                                                                                                        begun as soon as possible after exposure.
                                                                                                                   C.   Suggested Post-exposure prophylaxis dosage
                                                                                                                        regimen: 400 mg PO Q6h for 24 hours, then
                                                                                                                        400 mg PO TID for 6 day,.
                                                                                                                   d.   Adverse effects include: teratogenicity,
                                                                                                                        possible embryotoxicity, reversible meet,-
                                                                                                                        cytic anemia, extravascular hemolysis,

                                                                                                                                    9

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Document 52 f:/Week-36/BX003203/DIAGNOSIS AND TREATMENT OF DISEASES 1991PORTABLE FIELD PERSONNEL SHOWER SYSTEMS/diagnosis and treatment of diseases of importanc:12179609281524
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003203
Unit = OTSG
Parent Organization = HSC
Folder Title = DIAGNOSIS AND TREATMENT OF DISEASES 1991PORTABLE FIELD PERSONNEL SHOWER SYSTEMS
Folder Seq # = 88
Subject = DIAGNOSIS AND TREATMENT OF DISEASES OF IMPORTANC
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 17-DEC-1996