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File: 123096_sep96_decls23_0008.txt
Page: 0008
Total Pages: 52

Subject: DIAGNOSIS AND TREATMENT OF DISEASES OF IMPORTANCE               

Unit: OTSG        

Parent Organization: HSC         

Box  ID: BX003203

Folder Title: DIAGNOSIS AND TREATMENT OF DISEASES  1991PORTABLE FIELD PERSONNEL SHOWER SYSTEMS                

Document Number:          1

Folder Seq  #:         88










                                     BRUCELLOSIS

            communicability                                                                                6. Pulmonary (15-25%):
             A.    Route: inhalation of infectious aerosols; ingestion of                                        cough
                   contaminated meat or dairy products; direct contact                                     7. Systemic (almost 100%):
                   with infected tissues, blood or lymph with abraded skin                                       fever
                   or mucous membranes.                                                                          night sweats
                                                                                                                 malaise
             S.    isolation of patients: body fluid precautions.                                                weakness
                                                                                                                 weight loss
             C.    Contact prophylaxis: none required.                                                     S.    Cutaneous (5%):
                                                                                                                 many non-specific findings such as erythema
             Incubation period:    2 - 3 weeks (one week to several                                              nodosum, eczematous rashes, vasculitis, maculo-
             months).                                                                                            papular rashes and petechiae.
       Ill.  Diagnosis:   systemic infection with protean manifestations;                              C.  Laboratory:
             no diagnostic clinical findings.     Exposure history is                                      1.    Hematology: anemia, leukopenia, thrombocytopenia
ogy:  culture of pathogen from blood, bone
             products or consumption of cheese; (2) exposure to animals,                                         marrow, fluids or tissue; special media, condi-
             livestock, meats.                                                                                   tions and precautions required.
                                                                                                           3. Serology: very helpful; IgM elevated in first 3
              A. Symptoms and signs:                                                                             weeks, followed by IgG after 3 weeks; titer >
                   1. osteoarticular    (20-85%):                                                                1:160 indicates past exposure.
                        arthralgias
                        myalgia                                                                        D. Radiology:
                        arthritis                                                                                CXR abnormal in patients who acquired infection by
                        spondylitis                                                                              aerosol: bilar adenopathy; peribilar infiltrates;
                        osteomyelitis                                                                            nodular lesions; lung abscess; pleural effusions;
                        tenosynovitis                                                                            pneumothorax.
                        bursitis
                        sacroileitis                                                                   E. Invasive procedures: not required for diagnosis; only
                   2. Neurological (2-5t):                                                                       required in therapy for focal suppurative com-
ications.
                        myelitis
                        paresis                                                         i              P. "Gold Standard:" isolation of pathogen or titer >
                        psychosis                                                                                1:160 with compatible epidemiologic and clinical
                        depression                                                                               findings.
                        headaches
                   3. Genitourinary (2-40%):                                                    IV. Duration:
                        unilateral epididymo-orchitis                                                 A.  Treated:    weeks to months.
                        pyelonephritis, acute interstitial nephritis,                                  B.  Untreated:   months, with up to 30% complications.
                          prostatitis, (very uncommon)
                   4.   Cardiovascular:                                                         V . Complications:    see signs and symptoms
                        endocarditis -   2% (most common cause of death)
                   5. Gastrointestinal:                                                         VI. Treatment:        A.   No complications: doxycycline loo g
                        hepatitis                                                                                          BID plus rifampin 600 Mg/day x 6 weeks.
                        nausea and vomiting                                                                           B.   Complications:   seek specialist input.
                        diarrhea                                                                                      C.   Treatment failure and relapses occur in
                        abdominal pain                                                                                     5%; most not due to drug resistance;
                                                                         retreat with initial regimen.
                        anorexia


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Document 52 f:/Week-36/BX003203/DIAGNOSIS AND TREATMENT OF DISEASES 1991PORTABLE FIELD PERSONNEL SHOWER SYSTEMS/diagnosis and treatment of diseases of importanc:12179609281524
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003203
Unit = OTSG
Parent Organization = HSC
Folder Title = DIAGNOSIS AND TREATMENT OF DISEASES 1991PORTABLE FIELD PERSONNEL SHOWER SYSTEMS
Folder Seq # = 88
Subject = DIAGNOSIS AND TREATMENT OF DISEASES OF IMPORTANC
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 17-DEC-1996