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File: 123096_sep96_decls1_0087.txt
Page: 0087
Total Pages: 109

Subject: DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS       

Unit: OTSG        

Parent Organization: HSC         

Box  ID: BX003203

Folder Title: DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS                                       

Document Number:          1

Folder Seq  #:         21












                    movement of a small number of representative patients to one or more
                    previously designated medical facilities. Evacuation of a few patients is
                    considered to have significant advantages over the movement of extensive,
                    specialized laboratory facilities to the affected area. Small mobile
                    laboratories cannot provide the wide range of services which probably will be
                    necessary but, under certain circumstances, such laboratories would be useful.

                    610.    On the first reasonable assumption that an increased disease incidence
                    is due to artificially-disseminated organisms, such an emergency patient
                    transfer program for diagnostic purposes should, if feasible, be instituted.
                    The receiving facility might be an established treatment facility equipped
                    specifically for the care of patients with infectious disease, or a
                    specialized research center. Ideally it would be staffed with specially-
                    trained personnel and have the capability to definitively identify pathogenic
                    organisms. An alternative solution would be to locate the facility in close
                    proximity to a supporting Laboratory. By bringing the patient to such a
                    facility, the medical service would be able co concentrate its best infectious
                                                                        -ca          -on confirming the
                    disease, clinical, radiological, and la'cLaz.Qc)p      pabilities
                    specific etiological diagnosis in the shortest possible time. Success or
                    failure in organizing the medical defence will depend on the rapidity and
                    accuracy of the diagnostic effort.

                    SPECIFIC IDENTIFICATION OF THE BW AGENT

s in the identification of the BW agent include:

                            a. Isolacion of the organism which is possible in one to two days for
                            some agents.

                            b. Decection Of toxin by mass spectroscopy, animal inoculation and
                            other methods.

                            c. Antibody detection (Specific IgM appears in three days).

                            d. Agent detection using sensitive assay methods such as ELISA or IFA.

                            e. Genome detection employing DNA probes.

                            f. Detection of metabolic products of the infectious or toxin agent in
                            clinical specimens.

                    RAPID IDENTIFICATION IN THE FIELD

                    612.    A militarily useful field system should be able to rapidly identify a
                    wide range of potential BW agents, from a wide variety of samples, under a
                    wide variety of@operating conditions. The rapid identification system must:

                            a. Identify the specific infecting agent to ensure differentiation
                            from similar agents which may have different medical or military
                            operational implications from the agent in question.

                            b. Be able to make this specific identification early in the disease
                            process, preferably in the incubation period, to permit early treatmat


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Document 109 f:/Week-36/BX003203/DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS/detection of medical defense against biological :1217960927452
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003203
Unit = OTSG
Parent Organization = HSC
Folder Title = DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS
Folder Seq # = 21
Subject = DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 17-DEC-1996