DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS

File: 123096_sep96_decls1_0046.txt
Page: 0046
Total Pages: 109

Subject: DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS       

Unit: OTSG        

Parent Organization: HSC         

Box  ID: BX003203

Folder Title: DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS                                       

Document Number:          1

Folder Seq  #:         21




                                                    UNCLASSIFIED



                 necroticans (pig-bel), (c) clostridial food poisoning. Fach of these syndromes has very


                 specific requirements for delivering inocula of C, @ges to specific sites to induce


                         and it is difficult to envision a general @o in which the sports or vegetative


                 organisms could be used as a biowarfare agent. 'nere are, however, at least 12 pmtein


                 toxins elaborated, and one or more of these could be produced, concentrated, and used as a


                 weapon. Waterbome disease is conceivable, but unmmly. The best available speculation


                 (based on        y no exploratory data with which to sharpen our conclusions) is that the


                 alpha toxin would be lethal by aerosol, This is a well-chamcterized, highly toxic


                 phospholipase C. Other toxins from the organism might be co-weaponized and enhance


                 effectiveness. For example, the epsilon toxin is neurotoxic in laboratory animals.


                        Clinical Features





                        The clinical picture of aerosolized f, @ngens alpha toxin would be expected to be


                 that of a serious acute pulmonary insult. Absorbed alpha toxin could produce vascular leak,

                 hemolysis, thrombocytopenia, liver damage, etc. Other toxins admixed could modify the


                 event.


                        B.    DIAGNOSIS


                        1, Rouflne Laborat= Findings

                                                                                        .-Y:
                                                                            CLP,SSIFIED 11
                                                                            ,,EC         ON:
                                                 UNCLASSI@IED

Document 109 f:/Week-36/BX003203/DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS/detection of medical defense against biological :1217960927452
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003203
Unit = OTSG
Parent Organization = HSC
Folder Title = DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIALS
Folder Seq # = 21
Subject = DETECTION OF MEDICAL DEFENSE AGAINST BIOLOGICAL
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 17-DEC-1996