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File: 121096_sep96_decls39_0007.txt
Subject: DIAGNOSIS AND TREATMENT OF EXOTIC DISHES
Unit: OTSG
Parent Organization: HSC
Box ID: BX003203
Folder Title: DIAGNOSOS AND TREATMENT OF EXOTIC DISEASES
Document Number: 1
Folder Seq #: 180
spore challenge.
In the present setting, 3 doses of the vaccine (at 0,2, and 4 week(
recommended for prophylaxis against inhalation anthrax. Given project
stocks, 2 doses, 0.5 ml each, administered subcutaneously on days 0 an
are recommended initially. A third dose should be given 2 or more we
the second as additional vaccine becomes available. Contraindications I
are sensitivity to vaccine components (formalin, alum, benzethonium ch
and/or history of clinical anffim. Reactogenicity is mild to moderate: 1
6% of recipients will experience mild discomfort at the inoculation site
Vto 72 hours (tenderness, erythema, edema, pruritis), while a smaller prc
(< 1 %) will experience more severe local reactions (potentially limiting
the extremity for 1-2 days); modest systemic reactions (myalgia, malaise
grade fever) are uncommon, and severe systemic reactions (anaphylaxis,
precludes additional vaccination) are rare. The vaccine should be stor@
refrigerator temperature (= frozen). ?
ANTIBIOTICIS
Choice of antibiotics for prophylaxis is guided b
that for treatment; i.e., it is relatively easy to produce
tetracycline-resistant organism in the laboratory. Therefore, if there is
information indicating that a biological weapon attack is imminent, initia
prophylaxis with ciprofloxacin (500 mg po bid), or doxycycline (100 mg
bid) is probably reasonable. If unvaccinated, a single 0.5 ml dose of va(
should be given subcutaneously. Should the attack be confirmed as antlli
antibiotics should be continued for at least 4 weeks in all exposed. In ad
two 0.5 ml doses of vaccine should be given 2 weeks apart in the unvacc
those previously vaccinated with fewer than 3 doses should receive a sine
7
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Document 24 f:/Week-36/BX003203/DIAGNOSOS AND TREATMENT OF EXOTIC DISEASES/diagnosis and treatment of exotic dishes:12069615360440
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003203
Unit = OTSG
Parent Organization = HSC
Folder Title = DIAGNOSOS AND TREATMENT OF EXOTIC DISEASES
Folder Seq # = 180
Subject = DIAGNOSIS AND TREATMENT OF EXOTIC DISHES
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 06-DEC-1996