RATIONALE ANTIBIOTICS PROPHYLAXIS AGAINST INHALATION ANTHRAX

File: 120396_sep96_decls28_0005.txt
Page: 0005
Total Pages: 8

Subject: RATIONALE ANTIBIOTICS PROPHYLAXIS AGAINST INHALATION ANTHRAX    

Unit: OTSG        

Parent Organization: HSC         

Box ID: BX003203

Folder Title: RATIONALE FOR ANTIBIOTICS IN PROPHYLAXIS AGAINST INHALATION ANTHRAX                             

Document Number:          1

Folder SEQ  #:          5



                                  !!CrtlnrT
                                  %) L          NCLASSIFIED
         however, such a strategy is fraught with additional problems
         (age how long is long enough, antibiotic-related toxicitisel

         ate.) I and in therefore not feasible. It than is necessary to

         supplement the suppressive effect of antibiotics with an active
         immune response which would serve to "mop up" the late-
         germinating vegetative forms from these sporms. Consequently,
         the presence of an active i=une.response, generated @ to

         exposure, offers the highest probability of survival. ?ailing

         that, initiation of vaccination in concert with antibiotics after

         exposure should enable an infected individual to generate an
         immune response that could react in a similar way, albeit with
         somewhat lass certainty. In the primats experiments su=arizod

         above, this strategy proved effective.

























                                        5
                             @c,rtinrt
                             %)LU          UNCLASSIFIED

Document 8 f:/Week-36/BX003203/RATIONALE FOR ANTIBIOTICS IN PROPHYLAXIS AGAINST INHALATION ANTHRAX/rationale antibiotics prophylaxis against inhala:11089615091429
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003203
Unit = OTSG
Parent Organization = HSC
Folder Title = RATIONALE FOR ANTIBIOTICS IN PROPHYLAXIS AGAINST INHALATION ANTHRAX
Folder Seq # = 5
Subject = RATIONALE ANTIBIOTICS PROPHYLAXIS AGAINST INHALA
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 08-NOV-1996