RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT 20 AUG 90

File: 120396_sep96_decls54_0007.txt
Page: 0007
Total Pages: 16

Subject: RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT 20 AUG 90          

Unit: OTSG        

Parent Organization: HSC         

Box ID: BX003201

Folder Title: OPERATION DESERT SHIELD RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT                            

Document Number:          1

Folder SEQ  #:         45






          (potentially limiting use of the extremity for 1-2 days); modest systemic
          reactions (myalgia, malaise, low-grade fever) are uncommon, and severe
          systemic reactions (anaphylaxis, which precludes additional vaccination) is rare.
          The vaccine must be stored at refrigerator temperature n@ frozen).

                ANTIBIOTICS

                If there is information indicating that a biological weapon attack is
          imminent, initiating prophyllaxis with oral dose of penicillin V (500 mg),
          tetracycline (500 mg), or ciprofloxacin (250-500 mg) is probably reasonable.
          Should the attack be confirmed as anthrax, continued antibiotic use, together
          with post-exposure vaccination (see below) is warranted.

                POST-EXPOSURE

                There is no experience in post-exposure prophylaxis for anthrax in
          humans. Limited data from experiments in aerosol-infected monkeys suggests
          that post-exposure prophylaxis with a 5-10 day course of antibiotics alone only
          delays onset of fatal disease. Combining antibiotics with vaccination, on the
          other hand, was protective. Therefore, we feel that oral penicillin V (500 mg
          qid), procaine penicillin (1.2 million units IM bid), or tetracycline (500 mg qid)
          for 5-7 days, combined with a single dose of vaccine (and a second 14 days
          later, if available), represents a reasonable approach. In the event that
          vaccination is unavailable, prolonged antibiotic therapy (2-3 weeks), with
          continued observation for clinical signs after antibiotic withdrawal, is suggested.




                                                   7      PUPAAFT

Document 16 f:/Week-36/BX003201/OPERATION DESERT SHIELD RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT/response to the biological warfare bw threat 20 :11229616342212
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003201
Unit = OTSG
Parent Organization = HSC
Folder Title = OPERATION DESERT SHIELD RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT
Folder Seq # = 45
Subject = RESPONSE TO THE BIOLOGICAL WARFARE BW THREAT 20
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 22-NOV-1996