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File: doc04_23.txt
(¼
peristalsis, possibly by sy~pathetic activation. A central nervous
system effect is also suggested.
Accidental aerosol exposures to SEB have produced a SYNDROME of
high fever, nausea, vomiting, diarrhea, and headache. These
SYMPTOMS are accompanied by a leukocytosis with bandemia and
scattered pulmonary infiltrates by CHEST X-RAY. A dry,
nonproductive cough is virtually universal and shaking chills
accompany the fever. The aerosol route of intoxication can also
cause shock, fluid and hemodynamic derangements, and possibly even
death. TREATMENT consists of supportive measures for pulmonary and
hemodynamic compromise. As a purely toxic phenomenon,
antimicrobials are not effective except in secondary nosocomial
infections. The few humans accidentally expostd to aerosolized SEB
have recovered with supportive care.
DIAGNOSIS can be assisted by finding the toxin in clinical
samples0
Staphylococc7sEnterotoxin A-D.
C~) 6---~ PROTECTION
7. (U) DECONTAMINATION
CHLORINE COMPOUNDS are powerful germicides with a wide spectrum
of activity, lack of toxic residuals, and low price. Like other
halogens, they are highly reactive with organic matter and must be
used either on clean surfaces or in high concentrations. They are
corrosive to metals and highly effective against bacterial spores
such as Bacillus anthracis. Clorox (5% sodium hypochlorite; full
strength household bleach) is an excellent disinfectant. Coxiella
burneti, the causative agent of Q fever, is not inactivated by 5%
Clorox but is inactivated by either 70% ethyl alcohol or 5%
chloroform after a contact time of 30 minutes.
APPROVED BY. P EPARED BY:
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