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File: doc04_23.txt
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    peristalsis, possibly by sy~pathetic activation.  A central nervous
    system effect is also suggested.
      Accidental aerosol exposures to SEB have produced a SYNDROME of
    high  fever, nausea,  vomiting,  diarrhea,  and  headache.    These
    SYMPTOMS  are  accompanied by  a  leukocytosis  with  bandemia  and
    scattered  pulmonary  infiltrates   by   CHEST   X-RAY.     A  dry,
    nonproductive  cough is  virtually  universal   and shaking  chills
    accompany the fever.  The aerosol route of intoxication can also
    cause shock, fluid and hemodynamic derangements, and possibly even
    death.  TREATMENT consists of supportive measures for pulmonary and
    hemodynamic   compromise.     As   a   purely   toxic   phenomenon,
    antimicrobials are not effective except in secondary nosocomial
    infections.  The few humans accidentally expostd to aerosolized SEB
    have recovered with supportive care.
      DIAGNOSIS  can be  assisted  by finding   the  toxin  in  clinical
    samples0
    Staphylococc7sEnterotoxin A-D.


C~) 6---~ PROTECTION


    7.  (U) DECONTAMINATION

      CHLORINE COMPOUNDS are powerful germicides with a wide spectrum
    of activity, lack of toxic residuals, and low price.     Like other
    halogens, they are highly reactive with organic matter and must be
    used either on clean surfaces or in high concentrations.    They are
    corrosive to metals and highly effective against bacterial spores
    such as Bacillus anthracis.   Clorox (5% sodium hypochlorite; full
    strength household bleach) is an excellent disinfectant.    Coxiella
    burneti, the causative agent of Q fever, is not inactivated by 5%
    Clorox  but  is inactivated  by  either  70%  ethyl  alcohol  or 5%
    chloroform after a contact time of 30 minutes.


    APPROVED BY.                     P EPARED BY:


                                 ¼.


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